NAD+ (nicotinamide adenine dinucleotide, oxidized form) is a ubiquitous coenzyme present in all living cells that serves as an essential electron carrier in cellular metabolism and a critical substrate for multiple families of regulatory enzymes. As a research reagent, NAD+ is used extensively in biochemical assays, enzyme kinetics studies, and cell biology experiments investigating energy metabolism, DNA repair, gene expression regulation, and cellular aging. NAD+ functions as a substrate for sirtuins (SIRT1-7), a family of NAD+-dependent deacylase enzymes that regulate histone acetylation, transcription factor activity, and mitochondrial biogenesis.
Additionally, NAD+ serves as the substrate for poly(ADP-ribose) polymerases (PARPs), enzymes critical for DNA damage detection and repair signaling. Researchers studying the NAD+ metabolome, including the interconnected biosynthetic pathways involving nicotinamide, nicotinic acid, nicotinamide riboside, and nicotinamide mononucleotide, rely on exogenous NAD+ as both a reference standard and an experimental variable in their analytical workflows. In cell culture applications, NAD+ supplementation studies have been used to investigate effects of coenzyme availability on mitochondrial complex I activity, oxidative phosphorylation efficiency, and cellular resistance to metabolic stress.
Coffee & Pepper Peptides provides NAD+ as a high-purity research-grade reagent with complete analytical documentation. This product is intended exclusively for laboratory use and is not intended for human or animal consumption or dietary supplementation.
FDA DISCLAIMER
The information provided on this website has not been evaluated by the U.S. Food and Drug Administration (FDA). None of the statements herein, nor any of the products offered, are intended to diagnose, treat, cure, or prevent any medical condition.
All products are supplied strictly as laboratory research reagents and are not for human consumption. We do not provide products to patients and do not make any claims regarding medical use.
Coffee & Pepper Peptides operates solely as a chemical supplier. It is not a compounding pharmacy and does not operate as a compounding facility under Section 503A of the Federal Food, Drug, and Cosmetic Act.




Jeremy –
I’ve been using the NAD+ Kit from Coffee & Peppers for a few weeks now and the difference in my daily energy has been unreal. I feel more focused, less drained, and overall just better throughout the day.
Jerry Mophy –
Really impressed with the quality of this NAD+ Kit. Everything arrived properly packaged and easy to use. You can tell Coffee & Peppers actually care about what they’re supplying.
Victor G –
I originally bought the NAD+ Kit to help with recovery and fatigue, and honestly it’s been one of the best purchases I’ve made this year. Shipping was fast, discreet, and the customer service was excellent too.
Rachel –
After trying different brands before, this is the first NAD+ Kit that genuinely felt premium. Smooth experience from ordering to delivery, and I’ve already recommended it to two friends.
Nick jeo –
Couldn’t be happier with my order from Coffee & Peppers. The NAD+ Kit has helped me feel more refreshed and productive, especially during busy work weeks. Definitely coming back for another order.